14.B Meiosis and genetic variability




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14.B.1 Significance of meiosis

14.B.2 Important differences between meiosis and mitosis

14.B.3 Segregation of genes

14.B.3.a independent assortment

More info: http://www.sumanasinc.com/webcontent/animations/content/independentassortment.html

14.B.3.b linkage

14.B.3.c recombination

More info: http://www.biostudio.com/d_%20Meiotic%20Recombination%20Between%20Linked%20Genes.htm

14.B.3.d single crossovers

14.B.3.e double crossovers

14.B.4 Sex-linked characteristics

14.B.4.a very few genes on Y chromosome

14.B.4.b sex determination

14.B.4.c cytoplasmic inheritance, mitochondrial inheritance

More info: http://www.learner.org/courses/biology/archive/animations/hires/a_humev5_h.html

14.B.5 Mutation

14.B.5.a general concept of mutation

14.B.5.b types of mutations (random, translation error, transcription error, base substitution, insertion, deletion, frameshift)

14.B.5.c chromosomal rearrangements (inversion, translocation)

14.B.5.d advantageous versus deleterious mutation

14.B.5.e inborn errors of metabolism

14.B.5.f relationship of mutagens to carcinogens

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